POLECAMY
Koszyk
Ocular Oncology
Wydawca:
Format:
epub, mobi, ibuk
“Ocular Oncology” reflects a broad scope of expertise based on many years of work of the Authors. It is worth pointing out that all the Authors are eminent and internationally recognized specialists in ophthalmic oncology, who shared their experience with the readers.
The book's great didactic value are numerous illustrations such as color photographs, photographs in infrared light and autofluorescence, ultrasound examinations and optical coherence tomography as well as fluorescein and indocyanine angiography. The publication is a unique proposition for ophthalmologists, oncologists, oncological surgeons, radiotherapists and residents specializing in described topics. The book is also available in Polish language.
Książka „Onkologia okulistyczna” jest odzwierciedleniem wieloletniej pracy i ogromnej wiedzy autorów – wybitnych międzynarodowych specjalistów – wnikliwych znawców tematu, którzy starali się przekazać swoją wiedzę czytelnikom. Ogromną wartość dydaktyczną książki stanowią bardzo liczne ryciny: barwne fotografie, fotografie w świetle bezczerwiennym i autofluorescencji, badania ultrasonograficzne i optycznej koherentnej tomografii oraz angiografia fluoresceinowa i indocjaninowa).
Publikacja to unikatowa propozycja dla okulistów, onkologów, chirurgów onkologicznych, radioterapeutów i studentów wiążących swoją przyszłość z tymi specjalizacjami. Jest dostępna również w języku polskim.
| Rok wydania | 2020 |
|---|---|
| Liczba stron | 564 |
| Kategoria | Onkologia |
| Wydawca | PZWL Wydawnictwo Lekarskie |
| ISBN-13 | 978-83-200-5955-7 |
| Numer wydania | 1 |
| Język publikacji | angielski |
| Informacja o sprzedawcy | ePWN sp. z o.o. |
Ciekawe propozycje
Spis treści
| Abbreviations XVI | |
| 1. History of ocular tumor radiotherapy in Krakow – Bożena Romanowska-Dixon, Barbara Jakubowska 1 | |
| 2. Genetic aspects of ocular tumours – Jakub Khzouz, Sarah E. Coupland 11 | |
| Introduction | 11 |
| Eyelid cancers | 11 |
| Basal cell carcinoma | 11 |
| Sebaceous carcinoma | 13 |
| Merkel cell carcinoma | 14 |
| Conjunctival cancers | 15 |
| Conjunctival squamous carcinoma and pre-invasive lesions | 15 |
| Conjunctival melanoma | 17 |
| Conjunctival lymphomas | 18 |
| Intraocular cancers | 19 |
| Medulloepithelioma | 19 |
| Retinoblastoma | 20 |
| Uveal melanoma | 22 |
| Vitreoretinal Lymphoma | 23 |
| Summary | 24 |
| 3. Immunology of ocular tumors – Martine J. Jager, Jinfeng Cao 27 | |
| Introduction | 27 |
| Immune checkpoint inhibitors | 27 |
| Uveal melanoma: effect of checkpoint inhibitors | 28 |
| Other therapies | 29 |
| Presence of inflammation in UM | 29 |
| Phenotype-genotype comparisons | 29 |
| Comparison to other tumors | 30 |
| Conjunctival melanoma | 31 |
| Side effects of treatment | 32 |
| Conclusions | 32 |
| 4. Eyelid tumors – Joshua Ford, Bita Esmaeli 35 | |
| Introduction | 35 |
| Overview of eyelid malignancies | 36 |
| Basal cell carcinoma (BCC) | 36 |
| Squamous cell carcinoma | 37 |
| Sebaceous carcinoma (SebC) | 37 |
| Periocular sweat gland carcinoma | 38 |
| Merkel cell carcinoma | 38 |
| Malignant hair follicle carcinoma | 39 |
| Eyelid melanoma | 39 |
| American Joint Committee on Cancer Staging (TNM) of eyelid malignancies | 40 |
| Surgical management | 40 |
| Basal cell carcinoma | 40 |
| Squamous cell and sebaceous cell carcinoma | 40 |
| Eyelid melanoma | 41 |
| Merkel cell | 41 |
| Sentinel lymph node biopsy (SLNB) | 41 |
| Adjuvant therapies | 42 |
| Topical therapies – Imiquimod (Aldara) | 42 |
| Targeted therapies | 42 |
| BRAF targeted therapy (vemurafenib, sorafenib, debrafenib) | 43 |
| Immune checkpoint inhibitors (pembrolizumab, ipilimumab, nivolumab, | 43 |
| Other therapies | 44 |
| Summary | 44 |
| 5. Conjunctival tumors – Bożena Romanowska-Dixon, Barbara Jakubowska 49 | |
| Benign conjunctival tumors | 50 |
| Vascular lesions of the | 60 |
| Pigmented | 69 |
| Congenital and acquired melanosis | 70 |
| Malignant conjunctival tumors | 76 |
| Conjunctival squamous intraepithelial neoplasia (CIN; also termed C-SIN) | 76 |
| Invasive conjunctival squamous cell carcinoma (SCC) | 76 |
| Conjunctival melanoma | 80 |
| Lymphoid tumors | 90 |
| Metastatic tumors | 94 |
| Secondary conjunctival tumors | 95 |
| Differential diagnosis of conjunctival tumors | 95 |
| Conclusion | 102 |
| 6. Uveal tumors 105 | |
| Iris cyst – Bożena Romanowska-Dixon, Barbara Jakubowska | 105 |
| Uveal nevi and melanoma – Bożena Romanowska-Dixon, Barbara Jakubowska | 123 |
| Iris nevus | 124 |
| Iris melanoma | 140 |
| Iris metastases | 161 |
| Ciliary body tumors – Bożena Romanowska-Dixon, Barbara Jakubowska | 166 |
| Ciliary body cyst | 166 |
| Ciliary body and peripheral choroidal melanoma | 168 |
| Ciliary body metastases | 175 |
| Ciliary body adenoma and ciliary body adenocarcinoma | 176 |
| Differential diagnosis of ciliary body tumors | 176 |
| Choroidal tumors | 181 |
| Choroidal hemangioma – Bożena Romanowska-Dixon, Barbara Jakubowska | 181 |
| Choroidal osteoma – Bożena Romanowska-Dixon, Barbara Jakubowska | 201 |
| Sclero-choroidal calcifications – Bożena Romanowska-Dixon, Barbara Jakubowska | 211 |
| Choroidal pigmented tumors – Bożena Romanowska-Dixon, Barbara Jakubowska, Izabella Karska-Basta | 215 |
| Management of ciliary body and/or choroidal melanoma | 277 |
| Surgical treatment – Bożena Romanowska-Dixon, Agnieszka Kubicka-Trząska | 277 |
| Endoresection of choroidal melanoma – Agnieszka Kubicka-Trząska | 277 |
| Exoresection – Bożena Romanowska-Dixon | 282 |
| Enucleation – Bożena Romanowska-Dixon, Barbara Jakubowska | 285 |
| Radiotherapy – Bożena Romanowska-Dixon, Barbara Jakubowska | 295 |
| Prediction of metastatic disease in patients with choroidal melanoma – Bertil | 314 |
| Intraocular metastases – Bożena Romanowska-Dixon, Barbara Jakubowska | 317 |
| Introduction | 317 |
| Diagnosis | 318 |
| Treatment | 319 |
| Examples of intraocular metastases | 320 |
| Leukemia – Bożena Romanowska-Dixon, Barbara Jakubowska | 339 |
| 7. Differential diagnosis of intraocular tumors – Barbara Jakubowska, Bożena Romanowska-Dixon, Izabella Karska-Basta 347 | |
| Use of optical coherence tomography in a differential diagnosis of uveal tumor | 353 |
| Lesions masquerading as uveal melanoma | 361 |
| Use of indocyanine angiography in a differential diagnosis of uveal tumors | 365 |
| 8. Retinal tumors – Bożena Romanowska-Dixon, Barbara Jakubowska, Joanna Kobylarz 369 | |
| Retinal tumors – Bożena Romanowska-Dixon, Barbara Jakubowska | 369 |
| Retinal glioma – Bożena Romanowska-Dixon, Barbara Jakubowska | 384 |
| Retinoblastoma – Joanna Kobylarz, Bożena Romanowska-Dixon | 408 |
| Introduction | 408 |
| Pathogenesis | 408 |
| Symptoms | 408 |
| Diagnosis | 410 |
| Clinical manifestation | 413 |
| Classification | 415 |
| Treatment | 417 |
| Post-treatment management | 421 |
| Prophylaxis | 422 |
| Summary | 423 |
| Intra-arterial chemotherapy for retinoblastoma – Christina Stathopoulos, Carol L. Shields | 423 |
| Congenital hypertrophy of RPE (CHRPE) – Bożena Romanowska-Dixon, Barbara Jakubowska | 430 |
| 9. Intraocular lymphomas – Agnieszka Kubicka-Trząska 455 | |
| Epidemiology, classification, and clinical characteristics | 455 |
| Diagnosis | 458 |
| Imaging in intraocular lymphoma | 459 |
| Treatment | 462 |
| Prognosis | 464 |
| 10. Retrobulbar Orbital Tumors – Jacek Składzień 467 | |
| Orbital anatomy | 467 |
| Diagnosing orbital tumor | 471 |
| Diagnosing and treatment orbital tumors | 473 |
| Imaging | 474 |
| Medical history | 474 |
| Selected orbital malignancies in the retrobulbar region | 475 |
| Dermoid cyst, epidermoid cyst and developmental cyst of the orbit | 475 |
| Cavernous hemangioma of the orbit | 475 |
| Capillary hemangioma | 476 |
| Lymphatic hemangioma of the orbit (venous-lymphatic malformation, vascular hamartoma) | 476 |
| Idiopathic orbital inflammation (IOI)(orbital ‘pseudotumorIgG-4’) | 477 |
| Astrocytoma (glioma) | 477 |
| Optic nerve meningioma | 478 |
| Lacrimal apparatus disorders | 479 |
| Metastases of orbital tumors | 479 |
| Surgical treatment | 480 |
| Summary – basic techniques for accessing tumors | 488 |
| Orbital exenteration | 488 |
| Rehabilitation after surgery | 489 |
| 11. Radiotherapy of ocular and orbital tumors – Beata Sas-Korczyńska 493 | |
| Radiotherapy – characteristics | 493 |
| Interaction of ionizing radiation with matter | 493 |
| Energy and dose | 496 |
| Biological effects | 496 |
| Dose fractionation | 497 |
| External Beam Radiation Therapy (EBRT) | 497 |
| Brachytherapy | 500 |
| Radiotherapy of ocular and orbital tumors | 501 |
| Radiotherapy purpose and techniques | 501 |
| Radiation dose | 502 |
| Side effects in the radiotherapy of ocular and orbital tumors | 504 |
| Eyelid dermatitis | 505 |
| Conjunctivitis | 505 |
| Dry eye syndrome | 505 |
| Side effects in the cornea (keratopathy) | 506 |
| Cataract | 506 |
| Side effects on the iris | 506 |
| Side effects in the retina (retinopathy) | 506 |
| Optic neuropathy | 507 |
| Side effects in the sclera | 507 |
| Conclusion | 507 |
| 12. Preparation of orbit material for histopathological examination – Jolanta Orłowska-Heitzman 511 | |
| 13. Pathology of orbital tumors – Dariusz 515 | |
| Introduction | 515 |
| Non-cancerous orbital lesions | 517 |
| Most common types of orbital tumors and tumor-like lesions | 519 |
| Tumors of the optic nerve and its sheaths | 519 |
| Peripheral nerve tumors and other neurogenic tumors | 522 |
| Other neurogenic tumors | 523 |
| Tumors arising from the muscular or adipose tissue, fibrohistiocytic tumors, and other mesenchymal tumors | 524 |
| Osseous and chondral tumors and tumor-like lesions | 525 |
| Tumors and other proliferative lesions of the lymphatic, hematopoietic and histiocytic systems | 527 |
| Malignant secondary and metastatic orbital tumors | 532 |
| 14. Experimental models to study metastasis in uveal melanoma – Martyna Elas 535 | |
| Cell culture and tumoroids | 535 |
| Animal models | 536 |
| CAM | 536 |
| Zebrafish | 537 |
| Rat, mouse and hamster | 539 |
| Rabbit | 540 |
| Transgenic models of UM | 541 |
| Conclusions | 541 |
| Index | 545 |
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